Prediction of protein-protein interfaces utilizing four residue properties.
- Upload a PDB file and specify the ID of the chain to analyze.
- Upload a multiple sequence alignment (MSA) file in FASTA format first. The first sequence in the MSA has to match the sequence in the specified PDB-chain to allow for a mapping of residue-positions. The MSA will be filtered rigorously and must contain at least 50 sequences after filtering to allow for a sound computation of residue conservation. Please note that files larger than 15 MB are not accepted.
- The results will be saved as a PDB file and will be sent by email. PresCont results are encoded as b-factors in the PDB-file. The higher the value, the more likely a specific residue is part of a protein interface.